Here would be my cast
Director: Quentin Tarantino or Frank Miller
Solid snake: Kurt Russel or Hugh Jackman
Liquid Sake: Ian Mckellen
Vamp: Johnny depp
Otacon:Hideo Kojima (ahh what the hell lol)
Meryl:Kate Beckingsale
Ocelot:Al Pacino
Ninja/Gray fox:Jet Li