Glad I'm not invested in RE. I can think of a few...Shadows of the Damned was the least likely offender, only problems with it being buggy and lacking in depth. Many of the newer Sonic games starting with '06, though to name some specifically I'd say Black Knight and Chronicles. Legend of Zelda: Twilight Princess was the biggest disappointment I've had, though Saints Row 3 and 4, Grand Theft Auto 5, and Metal Gear Solid: Ground Zeroes are all very close for various reasons.