Final Fantasy XIII, as far as main series goes. I doubt I'll play it anytime soon as I don't own PS3, or XBox 360 for that matter, not that I would if I did as I don't find it appealing at all.

As for spin offs, Tactics Advance 2, Revenant Wings, Mystic Quest...I think that's about it, don't think anyone would blame me if I never play them which is exactly what I'll do.