Vista's the same way as 7, just click on "Remind Me in 4 Hours" and I don't get prompted to restart again.

Avast updates their database almost every day, if not more, no reboot required. I do have to restart if their's a newer version of the program itself that gets installed though.

As for some some mandatory system updates, I could really use the following:

Intel Core i7 930 CPU
Asus Rampage IV X58 LGA 1366 mainboard
6GB Corsair Dominator DDR3 memory kit
2x Asus or EVGA GeForce GTX 470 GPUs

Any donations for such from TFF would be greatly appreciated.