I love Mario Kart DS. Feels like the most balanced. My roommates off and on have a Wii and practically play Mario Kart Wii exclusively on it. I can't stand it, feels like one big unresponsive cluster****. Even when they play they spend the whole time yelling about how unfair the items and levels are and how they'll never play it again. All three have collectively played a solid 500 last games.

I always play Dry Bones in a standard kart.

To throw a wrench in the thread, I've always felt that Crash Team Racing was vastly superior to Mario Kart 64. Get at me.