For mine I usually do a base sketch, which I then ink with black fineliner 5,3, and 1 (5 being the thickest, 1 being the finest, although depending on the sive and detail of the image, I may just use 3 and 1 or just 1).
With colouring, I normally use Copic Ciao pens or colour on the computor. Copic Ciao pens (and other manga pens like them), are expensive at £2.50 per pen (about $1.75US at a guess), however if you have the money to spend on them and if you draw regularly, or are thinking about going into the design industry, they are a good investment. Say there is one area I want to colour blue, I will start with the lightest blue I need, and then apply the shading with each darker shade.
If you want to do digital colouring, then using a graphics tablet with Adobe Photoshop CS3 or CS4 (CS2 works well too, but I tend to use CS3) is the best option. Again, a graphics tablet and the software are expensive (although there are illegitemate ways of getting software, you just need to be careful and probably get assistance from someone who knows what is harmful or not), but the tablet will help simulate a pen and pad. It takes a while to get used to, but so does anything.
When colouring digitally, the first thing I will do is clear up the scanned in lineart. To do this, first adjust the levels to make the lines more defined, and then carefully use the eraser tool to tidy up any mess. Next, make a new layer to apply the base colour, or if the image has a lot of depth, a layer for each main base colour or segment. When colouring digitally, you may accidently leave areas colourless, so it is useful to make a few extra layers of blank colours (normally a dark blue and a terracotta) to help show up any patchyness. Once you have the base colour, start adding your basic details. Next comes shading, starting from the lightest up until the darkest. Next, do the highlights from the darkest to the lightest.
I hope that helps. I'm not great at explaining things, but if you want me to show you pictures of each step I use I can happily do that.
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